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Pluripotent stem cells that induce repair and regeneration of myocardial infarction
专利权人:
国立大学法人東北大学;株式会社Clio;株式会社Clio;国立大学法人岐阜大学
发明人:
吉田 正順,湊口 信也,出澤 真理
申请号:
JP2014530568
公开号:
JP5968442B2
申请日:
2013.08.15
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
An object of the present invention is to provide a novel medical application for use in regenerative medicine that uses pluripotent stem cells (Muse cells). The present invention provides a cell preparation for treating myocardial infarction, and particularly serious massive myocardial infarction and heart failure associated therewith, that contains pluripotent stem cells positive for SSEA-3 isolated from biological mesenchymal tissue or cultured mesenchymal cells. The cell preparation of the present invention is based on a cardiac tissue regeneration mechanism by which Muse cells are made to selectively accumulate in damaged myocardial tissue and differentiate into cardiac muscle in that tissue as a result of intravenous administration of Muse cells to a subject presenting with the aforementioned disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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