HLA-A2 restricted antigen peptide and use thereof

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专利权人:

国立大学法人愛媛大学

发明人:

安川 正貴,藤原 弘,越智 俊元

申请号：

JP2007139441

公开号：

JP5279063B2

申请日:

2007.05.25

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To provide an HLA-A2 restrictive antigen peptide. <；P>；SOLUTION: Provided is the HLA-A2 restrictive antigen peptide originated from Aurora-A and comprising an amino acid sequence of YLILEYAPL. An Aurora-A specific CD8+T-cell activated with the antigen peptide recognizes the antigen peptide bound HLA-A2 molecule on cells, exhibits cytotoxicity, and can attack malignant tumor cells expressing Aurora-A. The peptide is useful in a medical treatment field for malignant tumors, such as cell immunotherapy or vaccine therapy. <；P>；COPYRIGHT: (C)2009,JPO&INPIT

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