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Nitrogen-containing bicyclic compounds active in chronic pain conditions
专利权人:
Neurotune AG
发明人:
Ghelardini, Carla,Martinelli, Marisa,Parini, Carlo,Ronzoni, Silvano
申请号:
BRPI0908495
公开号:
BRPI0908495A2
申请日:
2009.02.17
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The invention refers to compounds of general formula (I) wherein the R groups are, independently, H, C 1-6 alkyl, aryl, CF 3 ; Y is CH 2 , C=O; X is bond, C=O, SO 2 , or C=N-CN; m is 0, 1; n is 0, 1; A is a heterocycle, or a phenyl group optionally substituted. The compounds are active on chronic pain conditions of different origin; they can be administered alone or with other drugs. Most of these compounds are new. The invention include a process to prepare said compounds, and pharmaceutical compositions suitable for their administration to a patient.
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