Kenneth M. Murphy,Theresa L. Murphy,John R. Sedy,Michelle A. Hurchla Pyles,Norihiko Watanabe,Jianfei Yang
申请号：
US13341611
公开号：
US20120207759A1
申请日:
2011.12.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides a novel lymphocyte inhibitory receptor termed BTLA which is expressed on both T and B cells, and identifies HVEM as interacting with BTLA. Methods and compositions for modulating BTLA-mediated signaling and interfering with the interaction of BTLA and HVEM for therapeutic, diagnostic and research purposes are also provided.
