Lorey, Susan,Janowski, Bernhard,Pultke, Heiko,Kathmann, Daniela,Parthier, Antje,Anton, Andreas
申请号：
AU2012357052
公开号：
AU2012357052A1
申请日:
2012.12.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to a proNGF mutant and to uses thereof, in particular the use of a proNGF mutant for producing human beta-NGF. The present invention discloses a method of preparing a biologically active human beta-NGF from an inactive insoluble proNGF mutant. A proNGF mutant of the invention is substituted by any amino acid but not Arg or Lys at the native protease cleavage site R
