Dan R. Littman,Jun R. Huh,Nicolas Gabriel Albert Manel,Daniel A. Ryan,David Y. Gin,Michael R. Krout
申请号:
US13989973
公开号:
US09505798B2
申请日:
2011.11.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Steroid compounds are disclosed that have a formula represented by the following:and wherein m, n, t, u1, u2, v1, v2, R1a, R1b, R2a, R2b, R3a, R3b, R3c, R3d, and Y are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the treatment or prevention of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.