Disclosed is a combination pharmaceutical composition comprising: a) a homeopathic activated-potentiated form of an antibody to S-100 protein, b) a homeopathic activated-potentiated form of an antibody to histamine, and c) a homeopathic activated-potentiated form of an antibody to TNF-alpha. Also disclosed is the use of such a composition in the preparation of one or more medicaments for the treatment of a disease or condition of functional etiology of the gastrointestinal tract.