The present disclosure describes implantable medical devices which include at least one tissue-gripping element, such as a barbed loop or a barbed and spiked nap. In certain embodiments, the implantable medical devices include a biocompatible substrate having a surface containing at least one barbed loop. The at least one barbed loop may protrude perpendicularly from the surface of the biocompatible substrate. In embodiments, a plurality of barbed loops may be positioned along any portion of the surface of the biocompatible substrate.
