A medical instrument includes a medical end effector and a user-actuated media transporter. The medical end effector includes an ultrasound propagating element and includes a path adapted for directing a medical agent, when conveyed therealong, to the ultrasound propagating element. The user-actuated media transporter is adapted for conveying the medical agent along the path and into contact with the ultrasound propagating element. A medical system includes a medical instrument and a user-actuated hemostatic-agent transporter. The medical instrument is adapted for treating patient tissue and is a mechanical-based ligation instrument or an energy-based ligation instrument. The user-actuated hemostatic-agent transporter is adapted for conveying a hemostatic agent to the patient tissue. A method for sealing a blood vessel of a patient includes applying a hemostatic agent to the blood vessel and includes treating the blood vessel with a medical instrument which is a mechanical-based ligation instrument or an energy-based ligation instrument.