COMPOSITIONS ET PROCÉDÉS POUR MODULER LES RÉPONSES IMMUNOLOGIQUES

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专利权人:

ZymoGenetics; Inc.

发明人:

申请号：

EP19207208.0

公开号：

EP3683230A1

申请日:

2006.05.12

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention provides a newly identified B7 receptor, zB7R1 that functions as lymphocyte inhibitory receptor, which is a PD-1-like molecule and is expressed on T cells. The present invention also provides the discovery of zB7R1's ability to bind to CD155. Methods and compositions for modulating zB7R1-mediated negative signaling and interfering with the interaction of its counter-receptor for therapeutic, diagnostic and research purposes are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/