WACKER Michael,WACKER Michael,WAECHTER Charles,WAECHTER Charles
申请号：
SI201031641
公开号：
SI2501406T1
申请日:
2010.11.16
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
The invention is directed to bioconjugate vaccines comprising N-glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus. The invention is further directed to N-glycosylated proteins containing an oligo- or polysaccharide having N-acetylgalactosamine at the reducing terminus and an expression system and methods for producing such N-glycosylated proteins.
