Glucokinase activators

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专利权人:

Merck Patent GmbH

发明人:

BURGDORF, Lars Thore,EMDE, Ulrich,GLEITZ, Johannes,BEIER, Norbert,CHARON, Christine

申请号：

ES09715751

公开号：

ES2581386T3

申请日:

2009.02.02

申请国别(地区):

ES

年份:

2016

代理人:

摘要：

Use of a compound selected from the group consisting of: {3 - [(4-methoxymethyl-thiophene-2-carbonyl) -amino] -5-methyl-pyrazol-1-yl} -acetic acid, {3- [ 4-Methyl-thiozol-2-carboxylic acid thiazol-2-ylamide (4-methoxymethyl-thiophene-2-carbonyl) -amino] -pyrazol-1-yl} -acetic acid, 5-methyl-thiophene-2-carboxylic acid, thiazole-2-ylamide Chloro-4-methanesulfonyl-thiophene-2-carboxylic acid, {5-methyl-3 - [(4-methyl-thiophene-2-carbonyl) -amino] -5 pyrazol-1-yl} - acetic acid, thiazol-2- 4- (4-Chloro-benzenesulfonyl) -thiophene-3-carboxylic acid ilamide, (4-methyl-thiazol-2-yl) -amide 5-propyl-thiophene-3-carboxylic acid, ethyl ester {2 - [(5-propyl-thiophene-3-carbonyl) -amino] -thiazol-4-yl} -acetic acid ethyl ester of 2 - [(5-propyl-thiophene-3-carbonyl) -amino] -thiazole- 4-carboxylic acid, 4-methyl-2 - [(5- propyl-thiophene-3-carbonyl) -amino] -thiazol-5-carboxylic acid, (1 H -imidazol-2-yl) -amide -propyl-thiophene-3-carboxylic acid, (1-pyridin-2-ylmethyl-1 H -pyrazol-3-yl) -amide 4-Methyl-thiophene-2-carboxylic acid, 5-methyl-1-pyridin-2-ylmethyl-1-pyrazin-2-ylmethyl-1-pyrazin-3-yl) -amide, (5-methyl-1 4-Methoxymethyl-thiophene-2-carboxylic acid pyridin-2-ylmethyl-1H-pyrazol-3-yl) -amide, 3-chloro-4-methanesulfonyl-thiophene-2-carboxylic acid thiazol-2-ylamide 4- (4-Chloro-phenyl) -thiophene-2-carboxylic acid thiazol-2-ylamide, 5-nitro-thiophene-3-carboxylic acid thiazol-2-ylamide, {2 - [(5-propyl- 4-Propyl-thiophene-3-carboxylic acid thiozole-3-carbonyl) -amino] -thiazol-4-yl} -acetic acid (1H-benzoimidazol-2-yl) -amide, 4-propyl-thiophene-3-carboxylic acid, thiazole-2-ylamide - (4-Chloro-benzenesulfonyl) -3-methyl-thiophene-2-carboxylic acid, 2 - [(5-propylthiophene-3-carbonyl) -amino] -thiazole-4-carboxylic acid, (1-pyridin-2-ylmethyl 4-Methyl-thiophene-2-carboxylic acid -1H-pyrazol-3-yl) -amide, [1,3,4] 5-propyl-thiophene-3-carboxylic acid thiadiazol-2-ylamide, (1H- [1,2,4] 5- Propyl-thiophene-3-carboxylic acid triazol-3-yl) -amide, thiazol-2-ylami gives 5

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