COMPOSITIONS PROMÉDICAMENTEUSES À PÉNÉTRATION ÉLEVÉE DE PEPTIDES ET DE COMPOSÉS APPARENTÉS À DES PEPTIDES

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专利权人:

CHONGXI;YU;YU, CHONGXI;TECHFIELDS BIOCHEM CO. LTD

发明人:

XU, LINA,CHEN, YUHUA,YAN, BINBING,TU, SHIQIAN,YU, CHONGXI

申请号：

EP10772043

公开号：

EP2427475A4

申请日:

2010.05.10

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Provided is a high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/