Howard Scalzo,Jerome A. Fischer,Stephen Rothenburger,Robert Cerwin,James R. McDivitt
申请号：
US13449184
公开号：
US20120199502A1
申请日:
2012.04.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof placing the containment compartment having the suture in an outer package and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
