Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists

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专利权人:

ObsEva S.A.

发明人:

Andre Chollet

申请号：

US15476325

公开号：

US10047048B2

申请日:

2017.03.31

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to a compound of formula (3Z,5S)-5-(hydroxymethyl)-1-[(2′-methyl-1,1′-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-meth19243yloxime, and/or an active metabolite thereof having antagonist action at the oxytocin receptor and/or vasopressin V1a receptor, to processes for their preparation, pharmaceutical compositions containing them and their use.

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