Some embodiments of the present disclosure include an anesthetic/analgesic composition for preventing or treating infections of the skin or muscle, insect bites, bruises, contusions, lacerations, burns, and other inflammatory conditions, including arthritic pain of joints. The composition may include water a member selected from the group consisting of ionic silver and nano-silver a phospholipid a di-glyceride a mineral oil a humectant a curcuminoid and optionally, menthol.