A drive sleeve (11) is arranged within a body (1) and coupled with a dose member (12) by means of threads (15, 16). Stop means (13, 14) inhibit a shift of the drive sleeve while allowing a rotation of the drive sleeve. A clutch (19) is provided to lock the dose member rotationally to the body in a releasable manner when a force is exerted on the dose member in the distal direction, the clutch permitting a movement of the dose member in the distal direction with respect to the body.