Compounds derived from urea, Kinase Inhibitors; Pharmaceutical composition that comprises; used in the treatment of diseases such as chronic Eosinophilic pneumonia, Asthma, COPD, Adult respiratory distress syndrome (ARDS), among others.
VAN NIEL MONIQUE BODIL,RAY NOCHOLAS CHARLES,PANCHAL TERRY AARON,JENNINGS ANDREW STEPHEN ROBERT,ARMANI ELISABETTA,CRIDLAND ANDREW PETER,ALCARAZ LILIAN,HURLEY CHRISTOPHER
申请号:
CL2014001486
公开号:
CL2014001486A1
申请日:
2014.06.06
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
Compounds of formula (I) and pharmaceutically acceptable salts thereof: wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.<;p>;COMPUESTOS DERIVADOS DE UREA SUSTITUIDO CON [1,2,4]TRIAZOL[4,3-A]PIRIDINILOXI, INHIBIDORES DE QUINASA P38; COMPOSICIÓ;N FARMACÉ;UTICA QUE LOS COMPRENDE; USO EN EL TRATAMIENTO DE ENFERMEDADES TALES COMO NEUMONÍ;A EOSINOFÍ;LICA CRÓ;NICA, ASMA, COPD, SÍ;NDROME DE ANGUSTIA RESPIRATORIA EN ADULTOS (ARDS), ENTRE OTRAS<;/p>;