NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE; MINISTRY OF HEALTH AND WELFARE
发明人:
黄琤,黃琤,蔡耿彰,黄钰玲,黃鈺玲,董明兆,黄琇珍,黃琇珍,陈旺全,陳旺全
申请号:
TW105117782
公开号:
TW201742628A
申请日:
2016.06.06
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
The present invention discloses an application of Helminthostachys zeylanica, ugonin and a compound as formula (I) for treating or preventing metabolic diseases including at least one from the group composed of the followings: metabolic syndrome, excessive fat accumulation, fatness, overweight, fatty liver, hepatic steatosis, hepatitis, cirrhosis, liver cancer, dyslipidemia, hyperlipidemia, hypertriglyceridemia, hyperlipoproteinemia, hypercholesterolemia, cardiovascular diseases, hyperglycemia, hyperinsulinemia, diabetes mellitus type 2, insulin resistance, insulin imbalance, glucose intolerance and their combinations.本發明揭示一種錫蘭七指蕨、入地蜈蚣素及式(I)化合物在治療或預防新陳代謝疾病之用途,包括代謝症候群、脂肪過度儲積、肥胖、體重過重、脂肪肝、肝性脂肪變性、肝炎、肝硬化、肝癌、血脂異常、高脂血症、高三酸甘油酯血症、高脂蛋白血症、高膽固醇血症、心血管疾病、高血糖症、高胰島素血症、第二型糖尿病、胰島素抗性、胰島素失調、葡萄糖耐受不良及其組合所組成之群組之至少一者。