Petrus Antonius van Rijn,Hendricus Gerardus Petrus van Gennip,Sandra Gerarda Petra van de Water,Femke Feenstra
申请号：
US14890994
公开号：
US09919044B2
申请日:
2014.05.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to methods for producing a propagation-competent strain of a mutant Reoviridae virus, and to a propagation-competent strain of a mutant Reoviridae virus that is obtainable by a method of the invention. The invention further relates to a propagation-competent strain of a mutant Reoviridae virus, comprising a deletion of a genetic region that is relevant for propagation of the virus, and to a vaccine, comprising a propagation-competent strain of a mutant Reoviridae virus.
