ANDERSEN, KIM VILBOUR,ANDERSEN, PETER SEJER,STRANDH, MAGNUS,KOEFOED, KLAUS,NIELSEN, LARS SOGAARD,PEDERSEN, MIKKEL WANDAHL,JACOBSEN, HELLE,KRAGH, MICHAEL,KJAER, IDA,POULSEN, THOMAS TUXEN,LANTTO, JOHAN
申请号:
CA2872226
公开号:
CA2872226A1
申请日:
2013.05.02
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one humanized anti-HER2 antibody and at least one humanized anti-HER3 antibody, and use of the antibody compositions for treatment of cancer. The invention also relates to the use of antibodies targeting multiple EGFR-family receptors to treat cancer (e.g., pancreatic cancer) and cancer that has acquired resistance to previous therapies.