THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
发明人:
RITTENHOUSE-OLSON, KATE
申请号：
CA2582252
公开号：
CA2582252C
申请日:
2005.07.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention is related to administration of monoclonal antibody JAA-Fl 1 toan individual for inhibition of metastasis and/or inhibition of growth ofcells which express TF~Ag, or for detection of tumors or metastatic foci whichexpress TF-Ag. For inhibition of metastasis or inhibition of growth of cellsexpressing TF-Ag, the method comprises administering to the individual atherapeutic amount of mAb JAA-F11, wherein the JAA-F11 mAb inhibits themetastasis and/or growth of the TF-Ag expressing cancer cells. For detectionof tumors or metastatic foci, mAb JAA-F11 is conjugated to a detectable labeland administered to the individual. Detection of the label identifiesmetatstatic foci or tumors which comprise cancer cells expressing TF-Ag.
