Pharmaceutical compositions are provided having an autotaxin inhibitor compound and an additional therapeutic agent such as anti-fibrotics, anti-inflamatory agents, anti-cancer agents, and cardiovascular agents.Linvention concerne des compositions pharmaceutiques ayant un composé inhibiteur de lautotaxine et un agent thérapeutique supplémentaire tel que des agents anti-fibrotiques, des agents anti-inflammatoires, des agents anticancéreux et des agents cardiovasculaires.