Shalini Gupta Prasanta Kalita Anshuman Dasgupta and
申请号：
IN3214/DEL/2014
公开号：
IN2014DE03214A
申请日:
2014.11.06
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention relates to a device and method for detection of bacterial lipopolysaccharides (LPS) in water or serum. The device comprises of a chemically-functionalized solid support for LPS capture from a target sample, antibiotic drugloaded gold nanoparticles (NPs) as detection probes and a signal-amplification silver reduction step to allow for visual detection of LPS by bare eye. This invention also relates to the use of such a device as a diagnostic kit for sepsis detection in critically ill/septicemia patients. This invention also relates to the use of such a device for LPS detection during pharmaceutical product testing, coliform bacterial contamination in potable water and drinks, sterility testing of reverse osmosis water used in dialysis and environmental water sample testing.
