PROBLEM TO BE SOLVED: To provide an anagenesis substrate excellent in invasiveness of cell, and suitable for regeneration of normal tissue.SOLUTION: In a tissue regeneration substrate comprising a nonwoven fabric composed of a bioabsorbable material, the nonwoven fabric has a pore size distribution measured by a bubble point method, in which the ratio of pores having the diameter of 5-30 μm is 70% or more, the ratio of pores having the diameter below 5 μm is 5% or less, and the ratio of pores having the diameter over 30 μm is 10% or less.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】細胞の侵入性に優れ、かつ、正常な組織の再生に好適な組織再生基材を提供する。【解決手段】生体吸収性材料からなる不織布からなる組織再生基材であって、前記不織布は、バブルポイント法により測定した孔径分布において、孔径5~30μmの孔の割合が70%以上、5μm未満の孔の割合が5%以下、かつ、30μmを超える孔の割合が10%以下である組織再生基材。【選択図】 なし