KUMAR-SINGH, RAJENDRA,KUMAR, BINIT,CASHMAN, SOIBHAN M.
申请号：
CA3090997
公开号：
CA3090997A1
申请日:
2019.02.11
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods and kits are provided for inhibiting inflammasome activation in cells of a subject or an inflammation- affected eye in a subject by administering to the subject a composition including a nucleotide sequence encoding a membrane independent CD59 protein operably linked to a promoter for expression and secretion of the membrane independent CD59 protein in the cells or the inflammation-affected eye thereby or a soluble CD59 protein the composition inhibiting inflammasome activation.
