A liquid atomization circuit for controlling a spray module that atomizes liquids is provided. The liquid atomization circuit includes a driving unit and a control unit. The driving unit can output a driving voltage so as to drive the spray module directly. The control unit is coupled to the driving unit to drive the driving unit so that the driving unit outputs a driving voltage. The spray module includes a first lead and a second lead. The first lead is coupled to the driving unit, and the second lead is coupled to the control unit. The control unit can output a predetermined voltage to the spray module.