Nitrogenous Heterocyclic Compounds, Pharmaceutical composition with AMPK activity; in vitro; methods; and its use in cardiovascular diseases, Type II diabetes, muscular dystrophy, neurolgicos disorders, inflammatory diseases, among others.
wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.COMPUESTOS DERIVADOS DE PIRIDINAS, CON ACTIVIDAD AMPK; COMPOSICION FARMACEUTICA; Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES, DIABETES TIPO II, DISTROFIA MUSCULAR, TRASTORNOS NEUROLÓGICOS, ENFERMEDADES INFLAMATORIAS, ENTRE OTRAS.