NON-INVASIVE SENSING OF FREE METAL IONS USING ION CHEMICAL EXCHANGE SATURATION TRANSFER

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专利权人:

THE JOHNS HOPKINS UNIVERSITY

发明人:

Amnon Bar-Shir,Jeff W.M. Bulte,Michael T. McMahon

申请号：

US14785486

公开号：

US20160091443A1

申请日:

2014.04.18

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention features a novel non-invasive approach for imaging, detecting and/or sensing metal ions with improved sensitivity and specificity in a biological sample or tissue. In certain embodiments, the invention provides a MR contrast-based approach for imaging, detecting and/or sensing metal ions in the biological sample/tissue containing various background ions by using 19F-based chemical exchange saturation transfer (CEST) technique.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/