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Methods for the development of vaccines based on oligosaccharide-oligonucleotide conjugates
专利权人:
Brandeis University
发明人:
Krauss Isaac J.,Hedstrom Lizbeth K.,MacPherson Iain S.
申请号:
US201514744985
公开号:
US10125162(B2)
申请日:
2015.06.19
申请国别(地区):
美国
年份:
2018
代理人:
LeClairRyan PLLC
摘要:
Described herein are oligosaccharide-oligonucleotide conjugates useful as vaccines against one or more human or veterinary therapeutic indications, and methods of synthesizing and identifying them. The conjugates may be identified using non-human antibodies as binding targets, thereby expanding the power and scope of the invention. Efficacious conjugates may be identified through an iterative screening process.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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