Krauss Isaac J.,Hedstrom Lizbeth K.,MacPherson Iain S.
申请号:
US201514744985
公开号:
US10125162(B2)
申请日:
2015.06.19
申请国别(地区):
美国
年份:
2018
代理人:
LeClairRyan PLLC
摘要:
Described herein are oligosaccharide-oligonucleotide conjugates useful as vaccines against one or more human or veterinary therapeutic indications, and methods of synthesizing and identifying them. The conjugates may be identified using non-human antibodies as binding targets, thereby expanding the power and scope of the invention. Efficacious conjugates may be identified through an iterative screening process.