OESTERGAARD, MICHAEL,SETH, PUNIT, P.,SWAYZE, ERIC, E.
申请号:
EP13845550
公开号:
EP2906256A4
申请日:
2013.10.11
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount, activity, or expression of the target nucleic acid in a cell. In certain embodiments, hybridization results in selective modulation of the amount, activity, or expression of a target Huntingtin gene or Huntingtin transcript in a cell.