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METHOD AND KIT FOR DETERMINING PROGNOSIS, REMOTE RECURRENCE RISK AND INVASION OF GLIOMA, AND PHARMACEUTICAL COMPOSITION FOR TREATING GLIOMA
专利权人:
SAPPORO MEDICAL UNIVERSITY
发明人:
Osamu HONMOU,Masahiko WANIBUCHI,Shunya OHTAKI,Masanori SASAKI,Yuko SASAKI,Nobuhiro MIKUNI
申请号:
US15748962
公开号:
US20190227067A1
申请日:
2016.07.28
申请国别(地区):
US
年份:
2019
代理人:
摘要:
[Problem] The present invention addresses the problem of providing a novel biomarker which makes it possible to find the prognosis of glioma, the risk of distant recurrence of glioma, the invasion ability of glioma cells and the like and also makes it possible to detect the prognosis, the risk, the invasion ability or the like in an earlier stage of a therapy of glioma.[Solution] The present invention relates to a method for evaluating the prognosis of glioma, said method comprising the steps of: detecting ACTC1 protein and/or mRNA encoding the protein in a glioma-containing sample collected from a patient; and determining that the prognosis of the glioma is poor when the ACTC1 protein and/or the mRNA encoding the protein is detected in the aforementioned step. According to the present invention, the prognosis of glioma, the risk of distant recurrence of glioma, the invasion ability and the like can be evaluated using a novel biomarker, i.e., ACTC1 protein and/or mRNA encoding the protein.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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