JAMES, SUSAN, P.,DEAN IV, HAROLD,DASI, LAKSHMI PRASAD,FORLEO, MARCIO, H.,POPAT, KETUL, C.,LEWIS, NICOLE, R.,PRAWEL, DAVID ALOIS
申请号：
EP13760533
公开号：
EP2825203A4
申请日:
2013.03.11
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM) and a guest molecule comprising hyaluronic acid wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.
