LI SHAOWEI,李少偉,WANG NAN,王楠,ZHANG XIAO,張曉,WANG KAIHANG,王凱航,ZHENG MINGHUA,鄭明華,XIA NINGSHAO,夏寧邵
申请号：
HK15105716.5
公开号：
HK1205148A
申请日:
2015.06.16
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present invention relates to the field of molecular biology and virology. In particular, the invention relates to a protein capable of being assembled in vitro into hepatitis E virus-like particles, a coding sequence and a preparation method thereof, and the virus-like particles comprising the protein the protein and the virus like particles can be used for the prevention of or for the treatment of HEV (hepatitis E virus) infection and diseases caused by the HEV, such as hepatitis E and the like. The invention also relates to use of the protein and the virus like particles in the preparation of pharmaceutical compositions and vaccines, the pharmaceutical compositions or the vaccines are used for the prevention or treatment of the HEV infection and diseases caused by the HEV, such as hepatitis E and the like. In addition, the invention also provides a preparation method of the HEV virus like particles.
