Michal Eisenbach-Schwartz,Nir Friedman,Kuti Baruch,Gilad Kunis,Liora Cahalon,Neta Rosenzweig,Aleksandra Deczkowska
申请号：
US14427089
公开号：
US20150238582A1
申请日:
2013.09.10
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method for treating a disease, disorder, condition or injury of the Central Nervous System (CNS) in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of an active ingredient, such as a non-encephalitogenic or weakly encephalitogenic combination of a Th1 adjuvant and a CNS-specific antigen, causing activation of the choroid plexus of said subject and maintaining said activation by reducing immunosuppression and establishing Th1-type immune response at the choroid plexus thus allowing either anti-inflammatory immune cells or immune cells which acquire a healing phenotype at the cerebrospinal fluid to pass through the choroid plexus, and accumulate at a site of damage in the CNS caused by said disease, disorder, condition or injury is provided.
