Andrew Paul May,Rachel E. Haurwitz,Jennifer A. Doudna,James M. Berger,Matthew Merrill Carter,Paul Daniel Donohoue
申请号:
US15904285
公开号:
US20180237770A1
申请日:
2018.02.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof. Genome engineering can refer to altering the genome by deleting, inserting, mutating, or substituting specific nucleic acid sequences. The altering can be gene or location specific. Genome engineering can use nucleases to cut a nucleic acid thereby generating a site for the alteration. Engineering of non-genomic nucleic acid is also contemplated.