The present invention is based on the discovery that the administration of atleast one immunoconjugate and at least one chemotherapeutic agent provides anunexpectedly superior treatment for cancer. The present invention is directedto compositions comprising at least one immunoconjugate and at least onechemotherapeutic agent and to methods of treating cancer using at least oneimmunoconjugate and at least one chemotherapeutic agent. The present inventionalso provides methods of modulating the growth of selected cell populations,such as cancer cells, by administering a therapeutically effective amount ofat least one chemotherapeutic agent and at least one immunoconjugate.