UTILISATION DE L'AGONISTE (1R-TRANS)(2.3-DIHYDRO-4-BENZOFURANYLE)CYCLOPROPYL]-METHYL]-PROPANAMIDE POUR LE TRAITEMENT DE TROUBLES DU RYTHME CIRCADIENS ET DU SOMMEIL

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专利权人:

INC.;VANDA PHARMACEUTICALS

发明人:

BIRZNIEKS, GUNTHER,PHADKE, DEEPAK,POLYMEROPOULOS, MIHAEL H.

申请号：

CA2666293

公开号：

CA2666293C

申请日:

2007.05.22

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

This invention provides the use of (1R-trans)-N-[[2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide as a melatonin receptor agonist to a humansubject to treat orprevent a circadian rhythm disorder or sleep disorder. More specifically, itdiscloses theuse of (1R-trans)-N-[[2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide(MA-1) for the preparation of a pharmaceutical composition for the treatmentof acircadian rhythm disorder or a sleep disorder, the pharmaceutical compositionbeingformulated for orally administering MA-1 to the subject suffering suchdisorder in anamount of about 20 mg to about 50 mg per day.

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中国工程科技知识中心

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http://www.ckcest.cn/home/