Brian Scott Ferguson,Hyongsok Tom Soh,David A. Hoggarth
申请号:
US14768134
公开号:
US20160166186A1
申请日:
2014.01.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides devices, methods and systems for analyte detection and/or monitoring, e.g., the continuous and/or semi-continuous monitoring of in-vivo analyte concentrations in real time. Generally, the devices, methods and systems of the present disclosure make use of signaling probes; methods or devices for reducing interferent-based fouling of the signaling probes, non-specific binding to the signaling probes and/or occlusion of a sensor surface; and methods and/or devices for providing an adjusted signal based on a detected signal from the signaling probes. Compositions including conformation switching signaling probes are also provided.