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COMPOUNDS HAVING TAFIA INHIBITORY ACTIVITY
专利权人:
LTD.;TAISHO PHARMACEUTICAL CO.
发明人:
AMADA HIDEAKI,MATSUDA DAISUKE,BOHNO AYAKO
申请号:
ZA201201528
公开号:
ZA201201528B
申请日:
2012.02.29
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The present invention provides compounds having superior TAFIa inhibitory activity. They are dihydroimidazoquinoline compounds represented by the following formula (I) or pharmaceutically acceptable salts thereof: wherein R is a hydrogen atom or a C1-10 alkyl group; R1 is a hydrogen atom, a C1-10 alkyl group, a C3-8 cycloalkyl group or a substituent having the structure represented by the following formula Ia or Ib: where R3 is a C1-6 alkyl group; R4 is a C1-6 alkyl group, a C3-8 cycloalkyl group, or a benzyl group; and R2 is a hydrogen atom or a substituent having the structure represented by the following formula Ic or Id:
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