QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS

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专利权人:

Qurient Co., Ltd.;Lead Discovery Center GmbH

发明人:

Kiyean NAM,Jaeseung KIM,Seohyun AHN,Yeejin JEON,Doohyung LEE,Dongsik PARK,Young-In YANG,SaeYeon LEE,Jeongjun KIM,Jiye AHN,Hana KIM,Chun-won JUNG,Carsten SCHULTZ-FADEMRECHT

申请号：

US15563123

公开号：

US20180093968A1

申请日:

2016.04.14

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to novel compounds which are inhibitors of TAM (Axl, Mer and Tyro 3) and/or Met family receptor tyrosine kinases (RTKs). These compounds are suitable for the treatment of disorders associated with, accompanied by, caused by or induced by a receptor of the TAM family, in particular a hyperfunction thereof. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly immune-suppressive cancer, refractory cancer and cancer metastases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/