The present disclosure concerns a shark-like chondroitin sulphate according to the formula shown, and a process for the preparation thereof. In particular, the present disclosure relates to a shark¬ like chondroitin sulphate, showing a very low amount of 4-sulphate(i.e. R4 is H), a high charge density and a biological activity comparable to natural chondroitin sulphates the disclosure also relates to a process for the preparation of said shark-like chondroitin sulphate affording substantially higher productivities and better reproducibility of product quality. The shark-like chondroitin sulphate of the disclosure shows a high molecular mass and charge density its in vitro biological and anti-inflammatory effectiveness, comparable to the ones of natural products make this polysaccharide potentially useful as a drug in pharmaceutical preparations and nutraceuticals.
