Two-step temperature profile for the propagation of viruses

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专利权人:

Manfred Reiter;Wolfgang Mundt;Leopold Grillberger

发明人:

Manfred Reiter,Leopold Grillberger,Wolfgang Mundt

申请号：

US12112261

公开号：

US08426124B2

申请日:

2008.04.30

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention provides a method for the production of a virus. The method includes providing a host cell that has been infected by the virus and cultivating the infected host cell at two different temperatures. The virus produced by the cultivation steps is subsequently collected. By using the dual temperature cultivation process, high titer and improved purity can be obtained.

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