<; p >; The present Invention provides a Therapeutic Agent and / or preventive, for example, to frontal lobe dysfunction (e.g., cognitive impairment (e.g.Cognitive impairment in Parkinson's disease, cognitive impairment caused by chronic stress, Dementia with Lewy bodies, Progressive Supranuclear Palsy, frontotemporal dementia,And similar), and others), Lewy body disease (For example, cognitive impairment in Parkinson's disease, Diffuse Lewy body disease, Dementia with Lewy bodiesMovement Disorder associated with Lewy body disease, and similar), and othersWhich contains a compound represented by the formula (i) or a pharmaceutically acceptable salts thereof as an active ingredient. <; / p >;USO DE N-[4-(2-FURIL)-5-(TETRAHIDROPIRAN-4-ILCARBONIL)TIAZOL-2-IL]-2-METILPIRIDINA-5-CARBOXAMIDA O UNA SAL FARMACÉUTICAMENTE ACEPTABLE PARA PREPARAR UN MEDICAMENTO ÚTIL PARA PREVENIR O TRATAR LA DISFUNCIÓN DEL LÓBULO FRONTAL Y ENFERMEDAD DE CUERPOS DE LEWY.