Yoon-Sun Yang;Ji Hyun Kim;Won Il Oh;Jong Wook Chang
发明人:
Yoon-Sun Yang,Won Il Oh,Jong Wook Chang,Ji Hyun Kim
申请号：
US13365022
公开号：
US08614191B2
申请日:
2012.02.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a pharmaceutical composition for the prevention or treatment of neurological disorders, comprising an ICAM-1 (intercellular adhesion molecule-1) protein, or a fragment or a variant thereof as an active ingredient, which can increase the expression of neprilysin to remove amyloid-beta (Aβ), a cause of dementia, and is thus useful in preventing or treating a neurological disease including Alzheimer's disease.
