It is described the use of L-carnitine, in combination with antioxidants such as vitamin E and inorganic elements such as manganese, zinc, sodium and potassium, for the preparation of a physiological supplement or medicament for opthalmic use, for the prevention or treatment of accomodative asthenopia.本發明描述L-肉鹼與抗氧化劑(諸如維生素E)及無機元素(諸如錳、鋅、鈉及鉀)之組合於製備供眼部使用以預防或治療調節性眼疲勞之生理補充品或藥品上的用途。