Bonnie L. Bassler,Lark J. Perez,Martin F. Semmelhack
申请号：
US14912207
公开号：
US09968587B2
申请日:
2014.08.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small molecule activators reduce virulence in V. cholerae. Acyl pyrrole molecules displayed strong potency and stability, particularly 1-(1H-pyrrol-3-yl)decan-1-one.
