Tso-pang Yao,Hitoshi Sasajima,Yoshiharu Kawaguchi,Kai Cui,Chun-Hsiang Lai
申请号:
US13129035
公开号:
US08664182B2
申请日:
2009.11.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibitor, and methyl pyruvate is also used in the methods. Dose packs comprising HDAC10 inhibitors and at least one second inhibitor are provided. Methods of identifying HDAC10 inhibitors are also provided.