Smith Ernest S.,Zauderer Maurice,Fisher Terrence Lee
申请号:
NZ63084713
公开号:
NZ630847A
申请日:
2013.03.27
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is an isolated synthetic scaffold peptide comprising (i) SEMA-4D conformational epitope formed by the three amino acid sequences set forth in SEQ ID NO:18 (LKVPVFYALFTPQLNNV), SEQ ID NO:20 (KWTSFLKARLIASRP) and SEQ ID NO:22 (EFVFRVLIPRIARV); and (ii) a chemical linker that joins the amino acid sequences, wherein an anti-SEMA4D antibody binds the SEMA4D epitope.