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NON-INVASIVE MAGNETIC OR ELECTRICAL NERVE STIMULATION TO TREAT GASTROPARESIS, FUNCTIONAL DYSPEPSIA, AND OTHER FUNCTIONAL GASTROINTESTINAL DISORDERS
专利权人:
Bruce J. Simon
发明人:
Bruce J. Simon,Joseph P. Errico,John T. Raffle
申请号:
US13731035
公开号:
US20130131753A1
申请日:
2012.12.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The methods provide damaged interstitial cells of Cajal (ICC) with trophic factors via vagal afferent nerve fibers, thereby reversing ICC damage, and as a consequence improving gastric motility. The methods also increase levels of inhibitory neurotransmitters in the brain so as to decrease neural activity within the area postrema, or they deactivate a resting state neural network containing parts of the anterior insula and anterior cingulate cortex, which will thereby reduce abnormal interoception and visceral hypersensitivity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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